SULPIRIDE 50mg

INGREDIENT:

Each hard capsule contains:

Sulpiride………………………..50 mg

Excipients:  Microcrystalline cellulose, magnesium stearate... just enough for 1 tablet.

POINT:

- Short-term treatment of anxiety symptoms in adults when they do not respond to standard treatments.

- Psychosomatic manifestations of gastric ulcer and duodenal ulcer.

DOSAGE - HOW TO USE:

- Short-term treatment of anxiety symptoms in adults: 50 - 150 mg/day, maximum 4 weeks.

- Psychosomatic manifestations of gastric ulcer and duodenal ulcer: take 1 pill/time, 3 times a day.

CONTRAINDICATIONS:

- Pheochromocytoma, acute porphyria.

- Hypersensitivity to any ingredient of the drug.

- Prolactin-dependent tumors such as pituitary adenoma and breast cancer.

- Combined with levodopa.

SPECIAL NOTES AND PRECAUTIONS WHEN USING:

- Use caution when using in the elderly due to high sensitivity to the drug.

- The drug is excreted by the kidneys, dosage should be carefully reduced and continuous treatment should not be used in patients with severe renal failure.

- Patients with epilepsy should be closely monitored because the drug can reduce the seizure threshold.

- Can be used but must be used with caution in Parkinson's patients.

Keep out of reach of CHILDREN.

USE FOR PREGNANCY AND LACTATION WOMEN:

- Pregnant women: Limit use during pregnancy and need to reduce dosage at the end of pregnancy.

- Excretion in breast milk is about 1/1000 of the daily dose.

DRUG INTERACTIONS, OTHER FORM OF INTERACTIONS:

- Contraindicated in combination with levodopa due to competitive antagonism. If sulpiride is necessary, the patient must discontinue levodopa.

- Avoid drinking alcohol or drinks containing alcohol because it increases the sedative effect of sulpiride.

- Note when combining with antihypertensive drugs: increases the antihypertensive effect and causes postural hypotension.

- Be careful when using with antidepressants, H1 antihistamines , barbiturates, sedatives, clonidine, and sleeping pills because they cause increased central nervous system depression.

EFFECTS ON ABILITY TO DRIVE AND OPERATE MACHINERY:

Sulpiride may reduce the patient's reflexes. Therefore, be careful when driving or operating dangerous machinery.

UNWANTED EFFECTS:

- Cardiovascular: postural hypotension. There are cases of QT prolongation and ventricular arrhythmia, which can lead to cardiac arrest and sudden death.

- Endocrine: Hyperprolactinemia, amenorrhea, galactorrhea, gynecomastia in men.

- Like other sedatives, sulpiride can cause malignant syndrome and weight gain.

- Hepatobiliary: very rarely increased liver enzymes.

- Nervous system: drowsiness, drowsiness, insomnia; extrapyramidal symptoms; Tardive dyskinesia with prolonged use.

Inform your doctor of any unwanted effects you encounter when using the drug.

OVERDOSAGE - TREATMENT:

Signs of overdose are signs of movement disorders.

Treatment is supportive and symptomatic.

PACKAGING:  Box of 10 blister packs x 10 tablets.

STORAGE:  Dry place, protected from light, temperature not exceeding 30  0 C.

QUALITY STANDARDS:  Manufacturer's standards.

SHELF LIFE:  36 months from date of manufacture.